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ラットにおけるVitaminE 欠乏症について : (第1報) 実験系の構成についての予備的検討
https://doi.org/10.60171/00003411
https://doi.org/10.60171/00003411c865c26f-2926-470b-a6ec-a8f46e7ec4e8
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||
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公開日 | 2023-03-15 | |||||||||
タイトル | ||||||||||
タイトル | ラットにおけるVitaminE 欠乏症について : (第1報) 実験系の構成についての予備的検討 | |||||||||
言語 | ja | |||||||||
タイトル | ||||||||||
タイトル | Vitamin E-Deficiency in Rats : 1. A preliminary Examination for the Establishment of Experimental Systems | |||||||||
言語 | en | |||||||||
言語 | ||||||||||
言語 | jpn | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | departmental bulletin paper | |||||||||
ID登録 | ||||||||||
ID登録 | 10.60171/00003411 | |||||||||
ID登録タイプ | JaLC | |||||||||
著者 |
伊東, 祥
× 伊東, 祥
× Ito, Nagako
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抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | The results of experimental studies on vitamin E-deficiency are largely affected by experimental conditions. This study, therefore, was undertaken to establish an exact experimental system for our further investigation of vitamin E-deprived rats. Wistar rats of either sex, weighing 40-60 g., were fed for a period from 12 to 25 weeks with a vitamin E-deficient diet mainly composed of corn starch, lard, casein (vitamin-free), dried yeast and salt mixture. The control animals were of two types; those fed with deficient diet but given oral supplements of alpha-tocopheryl acetate (30mg. daily) and those reared with a commercial stock diet. The growth curve of the experimental group shows that there was almost normal gain during the first 8 weeks, but from the 10th until the 19th week, retardation of the increase in body weight was apparent, and since then the body weight began to decrease most. Some changes were also observed in the general appearance of the rat deficient in vitamin E. The histological examination revealed pathological changes in the tissues of central nervous system, muscle, liver, skin and genitals. However, as to these several lesions, we could not deny the possibility that other causative factors than vitamin E-deficiency might also be concerned with such microscopic changes. We have obtained some valuable observations on adequate experimental conditions of breeding method or nutrition, which would make a significant contribution to our further experiments. | |||||||||
書誌情報 |
広島文化女子短期大学紀要 巻 1, p. 83-91, 発行日 1966-12-20 |
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出版者 | ||||||||||
出版者 | 広島文化女子短期大学 | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 09137068 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AN00213869 | |||||||||
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内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
著者版フラグ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |